Eugene Kholmovski, Ph.D.

REVIEWED PUBLICATIONS (selected)

  • Higuchi, K., Akkaya, M., Koopmann, M., Blauer, J.J., Burgon, N.S., Damal, K., Ranjan, R., Kholmovski, E., Macleod, R.S., & Marrouche, N.F. The effect of fat pad modification during ablation of atrial fibrillation: Late gadolinium enhancement MRI analysis. Pacing Clin Electrophysiol. 2013; doi: 10.1111/pace.12084. PMID: 23356963

  • Minalga E., Payne, A., Merrill, R., Todd, N., Vijayakumar, S., Kholmovski, E., Parker, D.L., & Hadley, J.R. An 11-channel radio frequency array coil for magnetic resonance guided high-intensity focused ultrasound of the breast. Magnetic Resonance in Medicine. 2013;69:295-302. PMC3382025

  • Volland, N., Kholmovski, E.G., Hadley, J.R., & Parker, D.L. Limited FOV MR thermometry using a local cardiac RF coil. Magnetic Resonance in Medicine. 2013; doi: 10.1002/mrm.24534.

  • Fitts, M., Breton, E., Kholmovski, E.G., Dosdall, D., Hong, K., Vijayakumar, S., Ranjan, R., Marrouche, N.F., Axel, L., & Kim, D. Arrhythmia insensitive rapid cardiac T1 mapping pulse sequence. Magnetic Resonance in Medicine. 2013; doi: 10.1002/mrm.24586. Abstract

  • Terry, C.M., Li, L., Li, H., Zhuplatov, I., Blumenthal, D.K., Kim, S.E., Owen, S.C., Kholmovski, E., Fowers, K.D., Rathi, R., & Cheung, A.K. In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis. Journal of Controlled Release. 2012;160:459-67. PMC3372620

  • Merrill, R.P., Hadley J.R., Minalga E., Kholmovski, E.G., Vijayakumar, S., Kim S.E., Quigley, E.P, Parker, D.L., & Rose, J. A 28-channel coil array for improved imaging of the optic nerve. Concepts in Magnetic Resonance Part B. 2012;41B:73-84. Abstract

  • Ranjan, R., Kholmovski, E.G., Blauer, J., Vijayakumar, S., Volland, N., Parker, D.L., MacLeod, R., & Marrouche, N.F. Identification and acute targeting of gaps in atrial ablation lesion sets using a real time MRI system. Circulation: Arrhythmia and Electrophysiology. 2012;5:1130-5. PMID: 23071143

  • Akkaya, M., Higuchi, K., Koopmann, M., Damal, K., Burgon, N., Kholmovski, E., McGann, C., & Marrouche, N. Higher degree of left atrial structural remodeling in patients with atrial fibrillation and left ventricular systolic dysfunction. Journal of Cardiovascular Electrophysiology. 2012; doi: 10.1111/jce.1. PMID: 23373748

  • Akoum, N., McGann, C., Vergara, G., Badger, T., Ranjan, R., Mahnkopf, C., Kholmovski, E., Macleod, R., & Marrouche, N. (2012). Atrial fibrosis quantified using late gadolinium enhancement MRI is associated with sinus node disfunction requiring pacemaker implant. Journal of Cardiovascular Electrophysiology. 23:44-50. PMID: 21806700

  • McGann, C., Kholmovski, E., Blauer, J., Vijayakumar, S., Haslam, T., Cates, J., DiBella, E., Burgon, N., Wilson, B., Alexander, A., Prastawa, M., Daccaret, M., Vergara, G., Akoum, N., Parker, D., Macleod, R., & Marrouche, N. (2011). Dark regions of no-reflow on late gadolinium enhancement MRI predict permanent scar formation after atrial fibrillation ablation. Journal of the American College of Cardiology. 58:177-185. PMID: 21718914

  • Adluru, G., Chen, L., Kim, S.E., Burgon, N., Kholmovski, E.G., Marrouche, N.F., & DiBella, E.V.R. (2011). Three-dimensional late gadolinium enhancement imaging of the left atrium with a hybrid radial acqusition and compressed sensing. Journal of Magnetic Resonance Imaging. 34:1465-1471. PMID: 21972108

• Minalga, E., Rose, J., Choi, S.E., Jeong, E.K., Kholmovski, E.G., Vijayakumar, S., Parker, D.L., & Hadley, R. (2011). A 20-channel coil for improved magnetic resonance imaging of the optic nerve. Concepts in Magnetic Resonance Part B. 39B:26-36.

• Daccarett M, Badger TJ, Akoum N, Burgon NS, Mahnkopf C, Vergara G, Kholmovski E, McGann CJ, Parker D, Brachmann J, Macleod RS, Marrouche NF.  Association of left atrial fibrosis detected by delayed-enhancement magnetic resonance imaging and the risk of stroke in patients with atrial fibrillation.  J Am Coll Cardiol. 2011 Feb 15;57(7):831-8.  PMID: 21310320

• Kuppahally SS, Akoum N, Badger TJ, Burgon NS, Haslam T, Kholmovski E, Macleod R, McGann C, Marrouche NF.  Echocardiographic left atrial reverse remodeling after catheter ablation of atrial fibrillation is predicted by preablation delayed enhancement of left atrium by magnetic resonance imaging.  Am Heart J. 2010 Nov;160(5):877-84.  PMC2995281

• Vergara GR, Vijayakumar S, Kholmovski EG, Blauer JJ, Guttman MA, Gloschat C, Payne G, Vij K, Akoum NW, Daccarett M, McGann CJ, Macleod RS, Marrouche NF.  Real-time magnetic resonance imaging-guided radiofrequency atrial ablation and visualization of lesion formation at 3 Tesla.  Heart Rhythm. 2011 Feb;8(2):295-303. Epub 2010 Oct 27.  PMID: 21034854

• Akoum N, Daccarett M, McGann C, Segerson N, Vergara G, Kuppahally S, Badger T, Burgon N, Haslam T, Kholmovski E, Macleod R, Marrouche N.  Atrial fibrosis helps select the appropriate patient and strategy in catheter ablation of atrial fibrillation: a DE-MRI guided approach.  J Cardiovasc Electrophysiol. 2011, 22(1):16-22.   PMID: 20807271

• Mahnkopf C, Badger TJ, Burgon NS, Daccarett M, Haslam TS, Badger CT, McGann CJ, Akoum N, Kholmovski E, Macleod RS, Marrouche NF.  Evaluation of the left atrial substrate in patients with lone atrial fibrillation using delayed-enhanced MRI: implications for disease progression and response to catheter ablation.  Heart Rhythm. 2010 Oct;7(10):1475-81. Epub 2010 Jul 1.  PMID: 20601148

• Samsonov AA, Velikina J, Jung Y, Kholmovski EG, Johnson CR, Block WF.  POCS-enhanced correction of motion artifacts in parallel MRI.  Magn Reson Med. 2010 Apr;63(4):1104-10.  PMC2852198

• Badger TJ, Daccarett M, Akoum NW, Adjei-Poku YA, Burgon NS, Haslam TS, Kalvaitis S, Kuppahally S, Vergara G, McMullen L, Anderson PA, Kholmovski E, MacLeod RS, Marrouche NF.  Evaluation of left atrial lesions after initial and repeat atrial fibrillation ablation: lessons learned from delayed-enhancement MRI in repeat ablation procedures.  Circ Arrhythm Electrophysiol. 2010 Jun 1;3(3):249-59. Epub 2010 Mar 24.  PMID: 20335558

• Kuppahally SS, Akoum N, Burgon NS, Badger TJ, Kholmovski EG, Vijayakumar S, Rao SN, Blauer J, Fish EN, Dibella EV, Macleod RS, McGann C, Litwin SE, Marrouche NF.  Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI.  Circ Cardiovasc Imaging. 2010 May;3(3):231-9. Epub 2010 Feb 4.  PMID: 20133512

• Badger TJ, Adjei-Poku YA, Burgon NS, Kalvaitis S, Shaaban A, Sommers DN, Blauer JJ, Fish EN, Akoum N, Haslem TS, Kholmovski EG, MacLeod RS, Adler DG, Marrouche NF.   Initial experience of assessing esophageal tissue injury and recovery using delayed-enhancement MRI after atrial fibrillation ablation.  Circ Arrhythm Electrophysiol. 2009 Dec;2(6):620-5.   PMID: 20009076

• Segerson NM, Daccarett M, Badger TJ, Shabaan A, Akoum N, Fish EN, Rao S, Burgon NS, Adjei-Poku Y, Kholmovski E, Vijayakumar S, DiBella EV, MacLeod RS, Marrouche NF.  Magnetic resonance imaging-confirmed ablative debulking of the left atrial posterior wall and septum for treatment of persistent atrial fibrillation: rationale and initial experience.  J Cardiovasc Electrophysiol. 2010 Feb;21(2):126-32. Epub 2009 Oct 5.  PMID: 19804549

• Oakes RS, Badger TJ, Kholmovski EG, Segerson NM, DiBella EVR, Fish E, Blauer JE, Akoum N, Daccarett M, Windfelder J, McGann CJ, Parker DL, MacLeod RS, Marrouche NF. Detection and quantification of left atrial structural remodeling using delayed enhancement MRI in patients with atrial fibrillation. Accepted to Circulation, 2009. PMC2725019

• Shi X, Kholmovski EG, Kim SE, Parker DL, Jeong EK. Improvement of accuracy of diffusion MRI using realtime navigated data acquisition. In press, NMR in Biomedicine, 2009. PMID19235143

• Mendes J, Kholmovski EG, Parker DL. Rigid-body motion correction with self navigated MRI. In press, Magn Reson Med, 2009. 61(3), 739–747, 2009 PDF

• Badger TJ, Oakes RS, Daccarett M, Burgon NS, Segerson NM, Akoum N, Fish EN, Rao SN, Blauer JE, Kholmovski EG, Vijayakumar S, DiBella EVR, MacLeod RS, Marrouche NF. Temporal left atrial lesion formation following ablation of atrial fibrillation: Lessons learned from delayed enhancement MRI. In press Heart Rhythm Journal, 2009. PMID19187904

• Adluru G, McGann C, Speier P, Kholmovski EG, Shaaban A, DiBella EVR. Acquisition and reconstruction of undersampled radial data for myocardial perfusion MRI. In press, J Magn Reson Imaging, 2009. PMC2720808

• Zhang L, Kholmovski EG, Guo JY, Kim SE, Morrell GR, Parker DL. HASTE sequence with parallel acquisition and T2 decay compensation: Application to carotid artery imaging. Magn Reson Imaging, 27:13-22, 2009. PMC2630054

• Payne AH, Goodrich KC, Kholmovski EG, Roemer RB, Parker DL. Isolated kidney phantom for development of bio-thermal vascular models with application to high intensity focused ultrasound therapy. Med Phys 35:4426-34, 2008. PMID18975689

• McGann CJ, Kholmovski EG, Oakes RS, Blauer JJE, Daccarett M, Segerson N, Airey KJ, Akoum N, Fish E, Badger TJ, DiBella EVR, Parker DL, MacLeod RS, Marrouche NF. New magnetic resonance imaging based method to define extent of left atrial wall injury after the ablation of atrial fibrillation. Journal of the American College of Cardiology, 52:1263-71, 2008.

• Kholmovski EG, DiBella EVR. Perfusion MRI with radial acquisition for arterial input function assessment. Magn Reson Med 57:821-7, 2007.

• Guo J, Kholmovski EG, Zhang L, Parker DL. Evaluation of motion effects on parallel MR imaging with precalibration. Magn Reson Imaging 25:1130-7, 2007.

• Zhang L, Kholmovski EG, Guo JY, Parker DL. TSE with average specific phase encoding ordering for motion detection and artifact suppression. J Magn Reson Imaging 25:1271-82, 2007.

• Guo J, Kholmovski EG, Zhang L, Jeong EK, Parker DL. K-space inherited parallel acquisition (KIPA): Application to magnetic resonance imaging thermometry. Magn Reson Imaging 67:903-15, 2006.

• Jeong EK, Kim SE, Kholmovski EG, Parker DL. High-Resolution DTI of a localized volume using 3D singleshot Interleaved Multiple Inner Volume Diffusion-Weighted STimulated EPI (3D ss-IMIV-DWSTEPI). In press, Magn Reson Med, 56:1173-81, 2006.

• Jeong EK, Kim SE, Guo J, Kholmovski EG, Parker DL. High-resolution DTI with 2D interleaved multislice reduced FOV single-shot EPI (2D ss-rFOV-EPI). Magn Reson Med 54:1575-9, 2005.

• Kholmovski EG, Parker DL. Application of phase consistency to improve time efficiency and image quality in dual echo black blood carotid angiography. Magn Reson Imaging 23:711-22, 2005.

• Vemuri P, Kholmovski EG, Parker DL. Coil sensitivity estimation for optimal SNR reconstruction and intensity inhomogeneity correction in phased array MR imaging. IMPI, LNCS 3565, p. 603-14, 2005.

• Kholmovski EG, DiBella EVR, Samsonov AA. Accurate assessment of the arterial input function using MRI with radial sampling. J Cardiovasc Magn Reson 7:292-4, 2005.

• Samsonov AA, DiBella EVR, Kellman P, Kholmovski EG, Johnson CR. Adaptive k-T BLAST/k-T SENSE for accelerating cardiac perfusion MRI. J Cardiovasc Magn Reson 7:277-8, 2005.

• Samsonov AA, Kholmovski EG, Parker DL, Johnson CR. POCSENSE: POCS-based reconstruction for sensitivity encoded MRI. Magn Reson Med 52:1397-1406, 2004.

• Kim SE, Kholmovski EG, Jeong EK, Buswell H, Tsuruda JS, Parker DL. Triple contrast technique in black blood imaging using double inversion preparation. Magn Reson Med 52:1379-87, 2004.

• Vemuri P, Kholmovski EG, Goodrich KC, Zhang L, Tsuruda JS, Parker DL. Statistical based approach for aneurysm volume measurements. J Magn Reson Imaging 20:340-6, 2004

• Samsonov AA, Kholmovski EG, Johnson CR. Image reconstruction from sensitivity encoded MRI data using extrapolated iterations of parallel projection onto convex sets. Proc. SPIE v.5032, p.1829-38, 2003.

• Kholmovski EG, Samsonov AA, Parker DL. Motion artifact reduction technique for dual-contrast FSE imaging. Magn Reson Imaging 20:455-62, 2002.

• Kholmovski EG, Alexander AL, Parker DL. Correction of slab artifact using histogram matching. J Magn Reson Imaging 15:610-7, 2002.

• Kholmovski EG, Parker DL, Alexander AL. A generalized k-sampling scheme for 3D Fast Spin Echo. J Magn Reson Imaging 11:549-8, 2000.